Research Articles
Stereochemistry in Drug Action: From Molecular Chirality to Clinical Outcomes
This article provides a comprehensive examination of stereochemistry's critical role in drug discovery and development, tailored for researchers, scientists, and drug development professionals.
Drug Receptor Theories: From Occupation Theory to Modern Clinical Applications
This comprehensive review explores the evolution of drug receptor theories, providing researchers and drug development professionals with both foundational knowledge and cutting-edge applications.
Structure-Activity Relationship (SAR) Studies: A Comprehensive Guide from Foundations to Modern Applications in Drug Discovery
This article provides a comprehensive overview of Structure-Activity Relationship (SAR) studies, a cornerstone of modern medicinal chemistry and drug discovery.
Navigating Drug-Like Space: The Central Role of Physicochemical Properties in Modern Drug Design
This article provides a comprehensive overview of the critical role physicochemical properties play in the entire drug discovery and development pipeline.
Principles of Rational Drug Design: A Modern Framework for Targeted Therapeutics
This article provides a comprehensive overview of the principles and practices of Rational Drug Design (RDD), a systematic approach that leverages knowledge of biological targets to develop new medications.
Hit to Lead (H2L) in 2025: A Strategic Guide to Accelerating Drug Discovery
This article provides a comprehensive overview of the Hit-to-Lead (H2L) process in modern drug discovery, tailored for researchers, scientists, and development professionals.
Target Product Profile (TPP): The Strategic Blueprint for Successful Drug Development
This article provides a comprehensive guide to Target Product Profiles (TPPs), a critical strategic planning tool in biomedical product development.
Druggability Assessment of Molecular Targets: Methods, Applications, and Future Directions in Drug Discovery
This comprehensive review explores the critical role of druggability assessment in modern drug discovery, addressing the high attrition rates in pharmaceutical development.
Target Identification and Validation in Drug Discovery: Foundational Concepts, Advanced Methods, and Future Trends
This article provides a comprehensive overview of the critical processes of target identification and validation in modern drug discovery.
Quantum Leaps: How Quantum Simulations Are Revolutionizing Drug Discovery and Material Science
Explore how quantum simulations are transforming drug discovery and material science through advanced molecular modeling and quantum computing capabilities.